A prosthetic cornea is often used after standard corneal transplant has failed on more than one occasion, chemical injury, Stevens-Johnson Syndrome, or in cases of severe ocular surface disease. In conditions such as these a prosthetic cornea may provide some visual improvement. The Boston Keratoprosthesis Type I is often the prosthesis of choice. Having been granted FDA approval in 1992 the Boston Keratoprosthesis is the most commonly used prosthetic cornea in the United States as well as worldwide with over 7,000 implanted to date. This prosthesis is made with clear plastic and inserted into a corneal graft. The postoperative course for patients needing this surgery is rather protracted and careful and attentive management is required to optimize their visual outcome.